Rl. Moss et al., PROGRESSIVE PAN-COLONIC FIBROSIS SECONDARY TO ORAL-ADMINISTRATION OF PANCREATIC-ENZYMES, Pediatric surgery international, 13(2-3), 1998, pp. 168-170
Most patients with cystic fibrosis require oral administration of panc
reatic enzymes to treat pancreatic insufficiency. Recent use of higher
-strength enzyme preparations in large doses has been found to be asso
ciated with fibrotic strictures of the colon. We report a case of panc
olonic fibrosis due to pancreatic enzyme use.