G. Holmstrom et al., NEONATAL RISK-FACTORS FOR RETINOPATHY OF PREMATURITY - A POPULATION-BASED STUDY, Acta ophthalmologica Scandinavica, 76(2), 1998, pp. 204-207
Purpose: The aim of the study was to evaluate possible neonatal risk f
actors for retinopathy of prematurity (ROP) in a population-based grou
p of preterm, very low birth weight, infants. Method: The main study g
roup included 202 single-born infants with a birth weight of 1500 gram
s or less, A group of 57 twins were also described. Selected risk fact
ors were extracted from the neonatal records. Results: Univariate anal
ysis revealed an association between ROP and respiratory distress synd
rome (RDS), bronchopulmonary dysplasia (BPD), septicaemia? intraventri
cular bleeding, and the use of ventilator as well as continuous positi
ve airway pressure. In a stepwise logistic regression analysis, howeve
r, only gestational age at birth, birth weight and BPD were significan
tly associated with ROP, Conclusion: Prematurity per se remains the st
rongest risk factor for ROP.