PSORIATIC-ARTHRITIS - RECOGNITION AND MANAGEMENT

Citation
In. Bruce et Dd. Gladman, PSORIATIC-ARTHRITIS - RECOGNITION AND MANAGEMENT, Biodrugs, 9(4), 1998, pp. 271-278
Citations number
49
Categorie Soggetti
Immunology,"Pharmacology & Pharmacy",Oncology
Journal title
Volume
9
Issue
4
Year of publication
1998
Pages
271 - 278
Database
ISI
SICI code
Abstract
Psoriatic arthritis is an inflammatory arthritis associated with psori asis, which is usually negative for rheumatoid factor. The disease dis plays a wide spectrum of articular and periarticular features which ma y progress with time. Although psoriatic arthritis was thought to be a benign condition, it is now clear that up to 20% of patients progress to significant joint damage and functional disability. Recently, seve ral predictors for progression have been described and suggest the nee d for earlier, more aggressive, use of therapy in these patients. The ideal treatment for psoriatic arthritis is unclear, and few randomised controlled trials have been reported to date in this condition. Prosp ective evaluation of the treatment of early disease is now required to assess the effect of current and future therapies on the clinical, ra diological and functional outcomes of this condition.