INSIGHTS INTO THE DEVELOPMENT OF POLYCYSTIC-OVARY-SYNDROME (PCOS) FROM STUDIES OF PRENATALLY ANDROGENIZED FEMALE RHESUS-MONKEYS

Authors
ABBOTT DH DUMESIC DA EISNER JR COLMAN RJ KEMNITZ JW
Citation
Dh. Abbott et al., INSIGHTS INTO THE DEVELOPMENT OF POLYCYSTIC-OVARY-SYNDROME (PCOS) FROM STUDIES OF PRENATALLY ANDROGENIZED FEMALE RHESUS-MONKEYS, Trends in endocrinology and metabolism, 9(2), 1998, pp. 62-67
Citations number
32
Categorie Soggetti
Endocrynology & Metabolism
Journal title
Trends in endocrinology and metabolism → ACNP
ISSN journal
10432760
Volume
9
Issue
2
Year of publication
1998
Pages
62 - 67
Database
ISI
SICI code
1043-2760(1998)9:2<62:IITDOP>2.0.ZU;2-X
Abstract
The developmental pathophysiology of polycystic ovary syndrome (PCOS) is unknown. However, prenatally androgenized female rhesus monkeys exh ibit ovarian and endocrinological features that mimic those found in w omen with PCOS. Thus, prenatal androgen excess may provide an etiology for hyperandrogenism and anovulation in adulthood.