Purpose: We present our experience with preoperatively administered hy
perbaric oxygen therapy to patients who have sustained significant the
rapeutic radiation induced soft tissue injuries and subsequently under
go planned abdominal intervention/surgery. Materials and Methods: From
February 1993 to May 1997, 5 patients with a history of complications
following therapeutic radiation were prospectively treated with hyper
baric oxygen before a planned abdominal operation. Results: All patien
ts had uneventful hospital courses. An additional procedure was eventu
ally necessary in 2 patients but with fewer radiation related problems
following hyperbaric oxygenation. Conclusions: Hyperbaric oxygenation
may improve postoperative outcomes when given before planned open ope
rations in patients with previous therapeutic pelvic irradiation and a
history of radiation related complications.