Pt. Zacharia et al., PENETRATING KERATOPLASTY WITH A VALVED GLAUCOMA DRAINAGE IMPLANT FOR CONGENITAL GLAUCOMA AND CORNEAL SCARRING SECONDARY TO HYDROPS, Ophthalmic surgery, 29(4), 1998, pp. 318-322
The simultaneous management of glaucoma and corneal opacification is s
ometimes required in infants with severe congenital glaucoma if timely
visual rehabilitation is to be achieved. A 1-month-old female infant
presented with an enlarged, protuberant, opaque cornea in each eye and
elevated intraocular pressure. An intrastromal, fluid-filled cleft wa
s noted in both corneas. It resolved over 3 weeks as corneal scarring
progressed. Peripheral corneal clearing allowed a view of an essential
ly normal anterior chamber. Penetrating keratoplasty and Ahmed (New Wo
rld Medical Inc., Rancho Cucamonga, CA) valve implant surgery with mit
omycin-C were performed simultaneously in the two eyes 1 month apart.
At 15 months of age, the patient's grafts were clear and the intraocul
ar pressure was well controlled in both eyes. One eye required multipl
e procedures for eventual glaucoma control. No postoperative overfiltr
ation occurred. The authors conclude that the use of a valved implant
should be considered in patients who require urgent simultaneous corne
al and glaucoma surgery for severe congenital glaucoma. This combinati
on may improve early postoperative control of aqueous outflow and posi
tively affect long-term graft survival in these difficult cases.