2-SUBSTITUTED 5-ACETYL-4-HYDROXYTHIAZOLES

5-acetyl-4-hydroxythiazoles bearing various substituents at position 2 of the thiazole ring have been obtained from the parent NH-BOC protec ted hydrazino-hydrazono derivatives of 2-thiazolin-4-ones by hydrogen chloride-promoted cleavage of the NH-BOC protected hydrate moiety. Thi s preparative procedure represents a simple, direct, high-yielding, ch eap, and ecological method for the synthesis of valuable products that can in turn be useful as versatile tools in organic chemistry.