GEODIAMOLIDE-H AND GEODIAMOLIDE-I, FURTHER CYCLODEPSIPEPTIDES FROM THE MARINE SPONGE GEODIA SP

Authors
TINTO WF LOUGH AJ MCLEAN S REYNOLDS WF YU M CHAN WR
Citation
Wf. Tinto et al., GEODIAMOLIDE-H AND GEODIAMOLIDE-I, FURTHER CYCLODEPSIPEPTIDES FROM THE MARINE SPONGE GEODIA SP, Tetrahedron, 54(18), 1998, pp. 4451-4458
Citations number
29
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
54
Issue
18
Year of publication
1998
Pages
4451 - 4458
Database
ISI
SICI code
0040-4020(1998)54:18<4451:GAGFCF>2.0.ZU;2-#
Abstract
Two new cyclodepsipeptides, geodiamolide H (3) and I (4), were isolate d from the marine sponge Geodia sp. The structures of 3 and 4 were det ermined by 2D NMR spectroscopy while the absolute stereochemistry of 4 was established by X-ray crystallography. Geodiamolide H 3 was cytoto xic to some human cancer cell lines. (C) 1998 Elsevier Science Ltd. Al l rights reserved.