A CONCISE TOTAL SYNTHESIS OF (-CURACIN A, A NOVEL CYCLOPROPYL-SUBSTITUTED THIAZOLINE FROM THE CYANOBACTERIUM LYNGBYA MAJUSCULA())

Authors
MUIR JC PATTENDEN G YE T
Citation
Jc. Muir et al., A CONCISE TOTAL SYNTHESIS OF (-CURACIN A, A NOVEL CYCLOPROPYL-SUBSTITUTED THIAZOLINE FROM THE CYANOBACTERIUM LYNGBYA MAJUSCULA()), Tetrahedron letters, 39(18), 1998, pp. 2861-2864
Citations number
25
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
18
Year of publication
1998
Pages
2861 - 2864
Database
ISI
SICI code
0040-4039(1998)39:18<2861:ACTSO(>2.0.ZU;2-8
Abstract
A total synthesis of (+)-curacin A 1 which features a facile and selec tive thioacylation ol the polyene amino-alcohol 2 with the benzotriazo le-derived cyclopropyl thioamide 3, leading to 15, as a key step is de scribed. (C) 1998 Elsevier Science Ltd. All rights reserved.