AN ULTRASTRUCTURE OF CELL-DEATH IN A PIG MELANOMA

Citation
M. Levkut et al., AN ULTRASTRUCTURE OF CELL-DEATH IN A PIG MELANOMA, Veterinarni medicina, 43(3), 1998, pp. 81-85
Citations number
18
Categorie Soggetti
Veterinary Sciences
Journal title
ISSN journal
03758427
Volume
43
Issue
3
Year of publication
1998
Pages
81 - 85
Database
ISI
SICI code
0375-8427(1998)43:3<81:AUOCIA>2.0.ZU;2-M
Abstract
A form of cell death was studied electronmicroscopically in the regres sive stage of 4 pigs melanoma. Basically, four types of cells were fou nd: macrophages, large granular lymphocytes, melanocytes, and melanoph ages. Morphological changes in cell death were most frequently observe d in the cytoplasm of tumour cells, in the form of dilatation of granu lar endoplasmic reticulum and/or vacuolation of cytoplasm close to the cell surface together with crater-like cavities. Rarely, condensation and margination of nuclear chromatin were observed without lesions in the cytoplasm. The above lesions are typical sings of cells undergoin g apoptosis.