Purpose. We studied the frequency of testicular microlithiasis (TM) in
a select group of otherwise healthy infertile men with abnormal semen
. Methods. We reviewed scrotal sonography records of 180 consecutive p
atients with abnormal semen who were referred for evaluation of male i
nfertility. The pampiniform plexus was evaluated for possible varicoce
le, and the testes were examined for the presence or absence of intrat
esticular calcifications and/or masses. Five patients with more than 5
echogenic foci per transducer field in either testis were identified.
The medical records and sonograms of this subgroup of patients were a
nalyzed. Results. Of the 180 patients, 5 (2.8%) had TM. Three patients
with TM had concomitant small varicoceles; 2 others had a history of
testicular maldescent. Two patients eventually became fertile. Conclus
ions. Our results indicate a higher than expected frequency of TM in o
therwise healthy infertile men. We speculate that the magnitude of hyp
ospermatogenesis in patients with TM is variable and may relate to bot
h the degree of testicular dysgenesis and the presence or absence of c
oncomitant scrotal pathology (eg, scrotal varicocele and cryptorchidis
m). (C) 1998 John Wiley & Sons, Inc.