EPIDERMOLYSIS-BULLOSA ACQUISITA AND HEPAT ITIS-C

Introduction. Epidermolysis bullosa acquisita is a bullous dermatosis. Its etiology remains unknown and the efficacy of its treatment is low . Observation. We report the first association between epidermolysis b ullosa acquisita, chronic hepatitis C and cryoglobulinemia, healing wi th interferon alpha and ribavirine, Discussion. We suggest a role For hepatitis C virus in the pathogenesis of epidermolysis bullosa acquisi ta. We suppose a synthezis of autoimmune antibodies in a dysimmune env ironment. Interferon alpha and ribavirine might be a new therapeutic a venue but further studies are necessary to confirm it.