OPTIMIZATION OF THE DWELL-TIME FOR THE QUANTITATIVE-ANALYSIS BY GAS-CHROMATOGRAPHY MASS-SPECTROMETRY

In this paper, the signal path in a mass spectrometer used as a detect or for gas chromatography in the selected ion monitoring mode is analy zed. The process involved an accumulation step that can be considered as a digital filter. Thus the Nyquist criterion alone is to be taken i nto account for the acquisition, by contrast to what appends with othe r detectors which require a higher number of acquired points to minimi ze the error during peak integration. This theoretical assumption was tested and accepted for three different levels of signal-to-noise rati o.