SYNTHESIS AND BIOLOGICAL-ACTIVITY OF SOME 2-(6-METHOXYNAPHTHYL) PROPIONAMIDO AZETIDINE-2-ONES

Authors
UDUPI RH KASINATH N BHAT AR
Citation
Rh. Udupi et al., SYNTHESIS AND BIOLOGICAL-ACTIVITY OF SOME 2-(6-METHOXYNAPHTHYL) PROPIONAMIDO AZETIDINE-2-ONES, Indian Journal of Heterocyclic Chemistry, 7(3), 1998, pp. 221-224
Citations number
6
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Indian Journal of Heterocyclic Chemistry → ACNP
ISSN journal
09711627
Volume
7
Issue
3
Year of publication
1998
Pages
221 - 224
Database
ISI
SICI code
0971-1627(1998)7:3<221:SABOS2>2.0.ZU;2-C
Abstract
The hydrazide of 2-(6-methoxy alpha-naphthyl)-propionic acid (Naproxen ) was converted to the Schiffs bases which in turn on reacting with ar yl and aryloxy acetyl chlorides yielded the corresponding azetidin-2-o nes (4-a-c and 5 a-t). Representative compounds screened for antituber cular activity were proved to be equipotent with streptomycin.