T. Mullner et al., THE USE OF NEGATIVE-PRESSURE TO PROMOTE THE HEALING OF TISSUE DEFECTS- A CLINICAL-TRIAL USING THE VACUUM SEALING TECHNIQUE, British Journal of Plastic Surgery, 50(3), 1997, pp. 194-199
A prospective clinical trial from January 1994 to February 1996 evalua
ted the efficacy of a vacuum sealing technique in dealing with sacral
pressure ulcers, acute traumatic soft tissue defects and infected soft
tissue defects following rigid stabilization of lower extremity fract
ures in 45 patients. Polyvinyl foam under negative pressure generates
an area of high contact forces at the wound/foam interface. This situa
tion appears to facilitate granulation tissue production while maintai
ning a relatively clean wound bed. In 84% (38/45) of the patients the
use of the vacuum sealing technique following irrigation and debrideme
nt decreased the dimensions of the initial wound, thus facilitating he
aling time and the eradication of any pre-existing infection. Wound cl
osure by granulation, secondary closure, or split thickness skin graft
ing was achieved in 35 wounds. The vacuum sealing technique is an effe
ctive option in the management of infected wounds.