Improving the daily practice of medicine requires making changes in pr
ocesses of care. In many circumstances, the most powerful way to make
such changes is to conduct small, local tests-Plan-Do-Study-Act (PDSA)
cycles-in which one learns from taking action. Learning in these cycl
es has much in common with learning from prudent clinical work, in whi
ch therapies are initiated under close observation and adjustments are
made as data and experience accumulate. For many system improvements,
PDSA cycles are more appropriate and informative than either formal s
tudies with experimental designs (such as randomized trials) or the me
re implementation of changes without reflection or evaluative measurem
ent. Physicians can encourage systemic improvement by endorsing and pa
rticipating in prudent, local tests of change in their own offices and
in the health care organizations in which they work. To do this, they
must understand the scientific value and integrity of such small-scal
e tests.