Ki. Ishibashi et al., LATENT CEREBRAL-ARTERY STENOSES ON MAGNETIC-RESONANCE ANGIOGRAPHY IN A PATIENT DIAGNOSED AS PROBABLE ALZHEIMER-DISEASE, PSYCHIATRY AND CLINICAL NEUROSCIENCES, 52(1), 1998, pp. 93-96
A 65-year-old woman with hypertension developed slowly progressive mem
ory disturbance and disorientation. She was diagnosed as having Alzhei
mer-type dementia according to clinical criteria. Later her cognitive
deterioration was noted to fluctuate in parallel to her blood pressure
. Magnetic resonance angiography and single photon emission computed t
omography showed bilateral middle cerebral artery stenoses and middle
cerebral artery watershed dominant hypoperfusion. It is postulated tha
t the patient's cognitive disturbance may have originated from vascula
r lesions.