NASAL VACCINES - FROM FUNDAMENTAL-CONCEPTS TO VACCINE DEVELOPMENT

Authors
LEMOINE D FRANCOTTE M PREAT V
Citation
D. Lemoine et al., NASAL VACCINES - FROM FUNDAMENTAL-CONCEPTS TO VACCINE DEVELOPMENT, STP PHARMA SCIENCES, 8(1), 1998, pp. 5-18
Citations number
121
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
STP PHARMA SCIENCES → ACNP
ISSN journal
11571489
Volume
8
Issue
1
Year of publication
1998
Pages
5 - 18
Database
ISI
SICI code
1157-1489(1998)8:1<5:NV-FFT>2.0.ZU;2-8
Abstract
This article reviews intracranial vaccination, with particular emphasi s on fundamental concepts and vaccine development. The lymphoid tissue of the upper respiratory tract is described in terms of morphology, h istology and cell phenotype. The hypothetical mechanisms of antigen sa mpling and pathways eliciting immune responses are discussed. The lite rature describing practical approaches to nasal vaccine formulation ar e summarized.