DESIGN AND SYNTHESIS OF SOME NEW C-2-SYMMETRICAL CHIRAL DISULFONAMIDES FROM AMINO-ACIDS AND THE APPLICATION IN DIETHYLZINC ADDITION TO BENZALDEHYDE

Authors
WANG JQ ZHONG M LIN GQ
Citation
Jq. Wang et al., DESIGN AND SYNTHESIS OF SOME NEW C-2-SYMMETRICAL CHIRAL DISULFONAMIDES FROM AMINO-ACIDS AND THE APPLICATION IN DIETHYLZINC ADDITION TO BENZALDEHYDE, Chinese journal of chemistry, 16(1), 1998, pp. 65-77
Citations number
32
Categorie Soggetti
Chemistry
Journal title
Chinese journal of chemistry → ACNP
ISSN journal
1001604X
Volume
16
Issue
1
Year of publication
1998
Pages
65 - 77
Database
ISI
SICI code
1001-604X(1998)16:1<65:DASOSN>2.0.ZU;2-P
Abstract
Nine C-2-symmetric chiral disulfonamides were designed and synthesized from L-valine, L-phenylalanine and L-leucine respectively via one-pot ring opening of aziridines. The application of these disulfonamides a s catalyst in the addition of diethyl zinc to benzaldehyde in three re agent systems: Ligand-Ti((OPr)-Pr-i)(4)-Et2Zn; Ligand-Ti((OPr)-Pr-i)(4 )-H2O-Et2Zn; Ligand-Et2Zn was also described.