A 51 year old male received an orthotopic transplant because of end st
age ischaemic heart disease, The donor was a healthy male teenager wit
h no history of arrhythmias or other cardiac conditions, The patient p
resented with haemodynamically stable tachycardia and, dyspnoea five w
eeks post-transplant, The ECG showed a regular tachycardia of 140 beat
s/min with a right bundle branch block morphology, left axis deviation
, and a QRS duration of 135 ms, There were independent P waves, captur
e, and fusion beats confirming the diagnosis of ventricular tachycardi
a. Endomyocardial biopsy showed moderate focal rejection that was thou
ght to be responsible for the: arrhythmia. During the following six mo
uths the patient had recurrent tachyarrhythmias; on each occasion the
ECG morphology was the same and there was no cellular rejection. The p
atient continued to have frequent hospital admissions with ventricular
tachycardia requiring Dc cardioversion despite the empirical use of a
miodarone, sotalol, disopyramide, and procainamide. Eighteen mouths af
ter transplantation the diagnosis of fascicular tachycardia was suspec
ted by ECG morphology and supported by successful termination with int
ravenous verapamil, The arrhythmia was successfully managed by radiofr
equency ablation. This patient shows that arrhythmias following transp
lantation are not always related to rejection, and that other potentia
lly reversible causes should be considered, particularly when the ECG
during arrhythmia conforms to a classic configuration.