BACKGROUND: Percutaneous microwave coagulation therapy (PMCT) is effec
tive for small liver tumors. To enhance the radicality of PMCT, we dev
eloped a sequential coagulation technique. METHODS: After inserting th
e first guide-needle under sonography, multiple needles were placed th
rough a disk-type introducer that was devised to guide needle puncture
at regular intervals, and microwaves were irradiated. Six patients, i
ncluding 4 with hepatocellular carcinoma and 2 with liver metastasis,
underwent this technique for tumors of 15 to 80 mm in diameter. RESULT
S: This technique can coagulate an area up to 60 mm in diameter in one
session. Insertion of multiple needles, ranging from 2 to 11, was suc
cessful without complications, Three patients undergoing curative PMCT
developed no tumor recurrence. The other 3 received incomplete PMCT d
ue to the large size end location of the tumor. CONCLUSIONS: This prel
iminary study indicates the efficacy of this technique to facilitate a
nd secure PMCT in selected patients with liver tumors. (C) 1998 by Exc
erpta Medica, Inc.