SEVOFLURANE COMPARED WITH HALOTHANE FOR TRACHEAL INTUBATION IN CHILDREN

We have studied 40 healthy children, aged 3-10 yr, undergoing adenoton sillectomy, in a double-blind, randomized study. Intubating conditions were assessed when the pupils had become small and central after inha lation induction with either 5% halothane and 60% nitrous oxide in oxy gen or 8% sevoflurane and 60% nitrous oxide in oxygen. The quality of tracheal intubation was graded according to ease of laryngoscopy, posi tion of the vocal cords, coughing, jaw relaxation and movement of limb s. Fewer children had significant vocal cord movement on laryngoscopy (P<0.01) and more had ideal intubating conditions when halothane was u sed (12 of 20 compared with seven of 20; ns). Time to reach the clinic al end-point for intubation was reached sooner with halothane (P=0.015 ). In all children the trachea was intubated successfully at the first attempt and all remained haemodynamically stable throughout induction .