PURPOSE: Our goal was to describe the CT findings before and after rad
iation therapy in a series of patients with laryngeal chondroradionecr
osis. METHODS: The CT studies obtained before and after radiation ther
apy in nine patients with the diagnosis of laryngeal chondroradionecro
sis were reviewed retrospectively. RESULTS: CT scans revealed abnormal
ities in all patients, A variable degree of laryngeal soft-tissue swel
ling was seen in eight of the patients. In four patients, cartilaginou
s abnormalities were visible initially, and appeared in three of four
other patients who had further follow-up CT studies, Six patients had
involvement of the thyroid cartilage; collapse of the thyroid cartilag
e was seen in two cases and gas bubbles were visible adjacent to the t
hyroid cartilage in three cases. Four patients with involvement of the
thyroid cartilage eventually underwent total laryngectomy, and one di
ed suddenly in severe respiratory distress. In all three patients with
arytenoidal involvement, anterior dislocation of this cartilage was s
een; in two of these patients, the adjacent part of the cricoid cartil
age showed some sclerosis, Two patients with arytenoidal necrosis (bot
h with cricoidal sclerosis) kept a functional larynx. In one case, cri
coidal sclerosis was seen in association with lysis of the thyroid car
tilage. CONCLUSION: The CT appearance of laryngeal chondroradionecrosi
s is nonspecific, but the diagnosis can be strongly suggested in cases
of sloughing of the arytenoid cartilage, fragmentation and collapse o
f the thyroid cartilage, and/or in the presence of gas bubbles around
the cartilage.