TELANGIECTATIC OSTEOSARCOMA OF THE SKULL BASE

We present a patient with a distinctive lesion of the skull base, whic h, at imaging, showed expansile destruction of the sphenoid bone, hemo rrhage with fluid-fluid levels, and contrast enhancement of a solid po rtion. These features ordinarily suggest either giant cell tumor or an eurysmal bone cyst; however, pathologic examination confirmed instead a rare variant of osteosarcoma of the telangiectatic type. Although im aging findings can indicate any of these possibilities, biopsy is an e ssential step in arriving at the diagnosis.