ANGIOSARCOMA ARISING IN A CHRONICALLY LYMPHEDMATOUS LEG

Citation
Sa. Sinclair et al., ANGIOSARCOMA ARISING IN A CHRONICALLY LYMPHEDMATOUS LEG, British journal of dermatology, 138(4), 1998, pp. 692-694
Citations number
8
Categorie Soggetti
Dermatology & Venereal Diseases
ISSN journal
00070963
Volume
138
Issue
4
Year of publication
1998
Pages
692 - 694
Database
ISI
SICI code
0007-0963(1998)138:4<692:AAIACL>2.0.ZU;2-A
Abstract
Cutaneous angiosarcoma is a rare aggressive tumour of capillary and ly mphatic endothelial cell origin. It presents as multiple purple and re d papules and nodules on the head and neck or the extremities. We repo rt an 86-year-old woman with angiosarcoma arising on her chronically l ymphoedematous right leg. The lymphoedema, secondary to chronic immobi lity, had developed gradually over 40 years. No other family members h ad lymphoedema. The patient presented with a plaque of friable tumour tissue on the lower right leg and dorsum of the foot, and satellite le sions on the knee and groin which initially appeared to be petechial h aemorrhages, The satellite lesions in the groin grew into tumour nodul es. There was no evidence of a preceding malignancy, nor any operative intervention to the affected limb or abdomen, Histological examinatio n of all tumour specimens revealed moderately to poorly differentiated angiosarcoma. She died within 5 months of the first appearance of the skin nodules.