Clinical decision-making in advanced cancer is a highly complex proces
s. Many factors are thought to influence this process arguably the mos
t important of these is the patient's own preference. Studies show tha
t most patients want to be fully informed as to their diagnosis and in
volved in clinical decision-making. However, the attitudes of healthca
re workers often preclude patient involvement. Studies have also shown
that acceptability of chemotherapy for minimal therapeutic gain diffe
rs markedly between patients depending on factors such as age, gender
and family status. It is clearly impossible to make decisions about wh
at is best for patients without involving them in the decision-making
process, Indeed, it could be argued that active patient participation
actually simplifies this process.