Objective: To assess the short-and long-term outcomes of vena cava fil
ter (VCF) placement for prophylaxis against pulmonary embolism in pati
ents at high risk due to trauma. Design and Setting: Case series at a
level I trauma center. Patients: Patients were considered for prophyla
ctic VCF placement if they met 1 of the injury criteria-spinal cord in
juries with neurologic deficit, severe fractures of the pelvis or long
bone (or both), and severe head injury-and had a contraindication to
anticoagulation. Intervention: Vena cava filters were placed percutane
ously by the interventional radiologists when the acute trauma conditi
on was stabilized following admission. Main Outcome Measures: Filter t
ilt of 14 degrees or more, strut malposition, insertion-related deep v
ein thrombosis, pulmonary embolism, or inferior vena cava patency. Res
ults: There were 132 prophylactic VCFs placed. A 3.1%, rate of inserti
on-related deep vein thrombosis occurred, all of which were asymptomat
ic. Filter tilt occurred in 5.5% of patients and strut malposition in
38%. Three cases of pulmonary embolism (1 fatal) occurred in a prophyl
actic VCF, and all patients had either filter tilt or strut malpositio
n. The risk of pulmonary embolism developing was higher in those patie
nts with filter tilt or strut malposition than in those who did not ha
ve these complications (6.3%, vs 0%; P=.05; Fisher exact test). The 1-
, 2-, and 3-year inferior vena cava patency rates (+/-SD) were 97%+/-3
%. Conclusions: Prophylactic VCF can be placed safely with an acceptab
le rate of insertion-related deep vein thrombosis and long-term inferi
or vena cava patency. Patients with prophylactic VCF remain at risk fo
r pulmonary embolism if the filter is tilted 14 degrees or more or has
strut malposition. In such patients, consideration should be given to
placing a second filter.