GAS-CHROMATOGRAPHIC ENANTIOMER SEPARATIONS OF CHIRAL PCB METHYL SULFONS AND IDENTIFICATION OF SELECTIVELY RETAINED ENANTIOMERS IN HUMAN LIVER

Authors
ELLERICHMANN T BERGMAN A FRANKE S HUHNERFUSS H JAKOBSSON E KONIG WA LARSSON C
Citation
T. Ellerichmann et al., GAS-CHROMATOGRAPHIC ENANTIOMER SEPARATIONS OF CHIRAL PCB METHYL SULFONS AND IDENTIFICATION OF SELECTIVELY RETAINED ENANTIOMERS IN HUMAN LIVER, Fresenius environmental bulletin, 7(5-6), 1998, pp. 244-257
Citations number
27
Categorie Soggetti
Environmental Sciences
Journal title
Fresenius environmental bulletin → ACNP
ISSN journal
10184619
Volume
7
Issue
5-6
Year of publication
1998
Pages
244 - 257
Database
ISI
SICI code
1018-4619(1998)7:5-6<244:GESOCP>2.0.ZU;2-B
Abstract
The enantiomers of eight atropisomeric PCB methyl sulfons were separat ed by chiral capillary gas chromatography, using a modified cyclodextr in as stationary phase. Two of these PCB derivatives, -methylsulfonyl- 2,2',3',4',5,6-hexachloro-biphenyl (3-132) and 3-methylsulfonyl-2,2',4 ',5,5',6-hexachlorobiphenyl (3-149), were detected in human liver samp les and showed high enantiomeric excesses. In addition, 3-methylsulfon yl-4,4'-DDE (MeSO2-DDE) and bis(4-chlorophenyl)sulfone (BCPS), were pr esent in human liver.