CONTRIBUTION TO THE QUANTIFICATION OF C-10-CHLOROPARAFFINES - PART I - FIRST TIME QUANTIFICATION OF C-10-CHLOROPARAFFINES WITH PURELY SYNTHESIZED CHLOROALKANES AS STANDARDS

An analytical method has been developed for determination of C-10-chlo roparaffines with 4-6 chlorine atoms in technical products and in fish oil samples. After clean-up with gel permeation chromatography and mi ni silica gel column a pre-quantification has been achieved by high re solution gas chromatography-electron capture detection (HRGC-ECD). Def inite identification and quantification has then been completed with h igh resolution gas chromatography-mass spectrometry using negative che mical ionization (HRGC-MS-ECNI). For the first time, pure C-10-chloroa lkanes with different degrees of chlorination (2,5,6,9-tetrachlorodeca ne-3 diastereoisomers, 1,2,9,10-tetrachlorodecane-1 diastereoisomer, 1 ,2,5,6,9-pentachlorodecane-2 diastereoisomers, and 1,2,5,6,9,10-hexach lorodecane-2 diastereoisomers) were used as standards. Average recover y with HRGC-ECNI was higher than 97%. The described method is recommen ded for routine analysis in official supervisions.