The pattern of sexually transmitted disease (STD) is the basis for des
igning surveillance of specific STD, their trends and syndromic manage
ment protocols. Two hundred and fifteen consecutive first-time STD cli
nic attenders at a teaching hospital in Bombay were recruited for the
study in October 1995. Thorough clinical examination and the following
investigations were done: wet mount, Gram stain, Giemsa stain, modifi
ed Thayer-Martin (MTM) medium culture, Fontana stain, Venereal Disease
Research Laboratory (VDRL), Treponema pallidium haemagglutination tes
t (TPHA), HBsAg and HIV. Ulcerative STD constituted 73.5% of total STD
while 15.8% were discharges and 10.2% were genital growths. Ulcers in
decreasing order of frequency were chancroid (51.9%), genital herpes
(29.1%) and syphilis (14.5). 76.5% of genital discharges were due to g
onococcal infection. The high rate of ulcerative STD is possibly an im
portant co-factor for the high HIV prevalence of 31.2% in Bombay. Of 1
82 patients tested for HBV, 16 (8.8%) were reactive for HBsAg, reveali
ng a high prevalence among STD attenders. A high co-relation of HBsAg
positive with either HIV or VDRL requires urgent attention for HBV int
ervention strategies in this population.