A new immunosensor integrated to a now system has been developed. It i
s based on magnetic immunoparticles immobilized on a solid-state trans
ducer using a magnetic field. The described technique renews the immun
oparticles reproducibly for each analysis allowing a good measurement
precision. The developed experimental approach permits the implementat
ion of an automated immunoassay that is quick (analytical cycle <30 mi
n) and sensitive in the micromolar concentration range. The system was
applied to the determination of rabbit immunoglobulin G as an analyte
model.