MORPHOLOGICAL FINDINGS IN GASTRIC AND DUO DENAL MUCOSA IN PATIENTS WITH VIBRATION DISEASE

Aim. Morphological study of gastric and duodenal mucosa in patients wi th vibration disease. Materials and methods, 64 patients with vibratio n disease stage I and II were examined endoscopically, histologically bacterioscopically and morphometrically irrespective of the presence o r absence of gastrointestinal complaints. Results, Erosive gastroduode nitis, non-erosive gastroduodenitis and gastritis, polyps in the stoma ch and gastric offer sere diagnosed in 19(29.7%), 40(62.5%), 2(3.2%) a nd 1(1.6%) patients, respectively. Small intestinal metaplasia occurre d in 22% of patients. Helicobacter pylori occurred most frequently in the antral part of the stomach (90.24%). Advanced dissemination often combined with metaplasia of the small bowel. Morphometrically, there w ere slight differences from relevant values in patients with chronic g astroduodenitis, who were not exposed to occupational hazards. Vibrati on disease patients exhibited impairment of duodenal vessels (large en dothelial nuclei, thick arteriolar walls) 2 times more frequently than controls. Conclusion. In vibration disease, gastric and duodenal muco sa, as a rule, shows signs of chronic gastroduodenitis.