We have studied the hypervariable D1S80 locus in 185 individuals from
five South American Indian tribes, integrating these results with prev
ious investigations. Three alleles (18, *24 and *30) were common to a
ll tribes, but their Frequencies varied between northern and southern
populations. Brazilian tribes have a high frequency of 30 (average 35
%) while in Argentinian and Chilean Indian populations this allele is
present, on average, in 7% of the chromosomes only. Allele 24, the mo
st common in other ethnic groups, was observed in 10% and 25% of north
ern and southern Amerindians respectively. Genetic distance and dendro
gram analyses placed the Argentinian and Chilean tribes closer to Braz
ilian Caucasians, suggesting non-Indian admixture among them.