GROWTH-CONTROL OF DIFFERENT FUSARIUM SPECIES BY SELECTED FLAVONES ANDFLAVONOID MIXTURES

The antifungal activity of five substituted flavones and their mixture s with unsubstituted flavone or a flavanone was tested on malt extract agar against five Fusarium spp. 4'-Methylflavone and 2',6'-dichlorofl avone showed the highest activity while 4'-benzyloxyflavone caused the lowest inhibition of all test substances. A significant increase in t he antifungal effect of the substituted flavones could be observed if mixtures in combination with the unsubstituted flavone or flavanone we re used. Some aspects of structure-activity relationships are discusse d.