Three methods of predicting the impact of weed interference on crop yi
eld and expected economic return were compared to evaluate th economic
importance of weed spatial heterogeneity. Density of three weed speci
es was obtained using a grid sampling scheme in 11 corn and 11 soybean
fields. Crop yield loss was predicted assuming densities were homogen
eous, aggregated following a negative binomial with known population m
ean and k, or aggregated with weed densities spatially mapped. Predict
ed crop loss was lowest and expected returns highest when spatial loca
tion of weed density was utilized to decide whether control was justif
ied. Location-specific weed management resulted in economic gain as we
ll as a reduction in the quantity of herbicide applied.