A NOVEL CLASS OF CONFORMATIONALLY RESTRICTED OLIGONUCLEOTIDE ANALOGS - SYNTHESIS OF 2',3'-BRIDGED MONOMERS AND RNA-SELECTIVE HYBRIDIZATION

Authors
NIELSEN P PFUNDHELLER HM WENGEL J
Citation
P. Nielsen et al., A NOVEL CLASS OF CONFORMATIONALLY RESTRICTED OLIGONUCLEOTIDE ANALOGS - SYNTHESIS OF 2',3'-BRIDGED MONOMERS AND RNA-SELECTIVE HYBRIDIZATION, Chemical communications, (9), 1997, pp. 825-826
Citations number
20
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
9
Year of publication
1997
Pages
825 - 826
Database
ISI
SICI code
1359-7345(1997):9<825:ANCOCR>2.0.ZU;2-A
Abstract
A novel 2',3'-bicyclic nucleoside 5 has been synthesised and incorpora ted into oligonucleotide analogues resulting in strong and selective b inding to an RNA complement.