Isolated endobronchial secondaries are reported usually as single case
s or in series from either specialist surgical or cancer units. The la
tter two are selected populations and are not a good guide to the true
frequency of occurrence of such isolated endobronchial secondaries. T
he incidence of such endobronchial secondaries in a 15 yr prospective
series is reported. Results of all fibre-optic bronchoscopies carried
out in the Blackburn, Hyndburn and Ribble Valley districts from 1981 t
o 1995 together with histology were recorded prospectively throughout
the period. These had been audited yearly throughout, the data were co
llated, and the individual records of cases of endobronchial secondari
es examined. A total of 3353 bronchoscopies were carried out in the ye
ars 1951-1995 inclusive. Of these, 1391 had visible endobronchial abno
rmalities, from which 1059 had positive endobronchial histology. Sixte
en of the 1059 (1.5%) were with endobronchial secondaries. Over the sa
me period eight bronchial carcinoids (none biopsied, but later surgica
lly resected) were encountered. Isolated endobronchial secondaries mad
e up a higher proportion of endobronchial histology than expected at 1
.5% and were twice as frequently found as bronchial carcinoids. The po
ssibility of endobronchial secondaries should always be considered in
those with a history of previous carcinomas at other sites.