TRIMETHYLCHLOROSILANE - A NOVEL ACTIVATING REAGENT IN NUCLEOTIDE SYNTHESIS VIA THE PHOSPHORAMIDITE ROUTE

Authors
DABKOWSKI W TWOROWSKA I MICHALSKI J CRAMER F
Citation
W. Dabkowski et al., TRIMETHYLCHLOROSILANE - A NOVEL ACTIVATING REAGENT IN NUCLEOTIDE SYNTHESIS VIA THE PHOSPHORAMIDITE ROUTE, Chemical communications, (9), 1997, pp. 877-878
Citations number
15
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
9
Year of publication
1997
Pages
877 - 878
Database
ISI
SICI code
1359-7345(1997):9<877:T-ANAR>2.0.ZU;2-G
Abstract
Trimethylchlorosilane (TMSCl) is a remarkably efficient activator in t he reaction of phosphorus(III) amides with nucleosides to give phospho rus(In) esters in excellent yield.