The purpose of this study was to review our experience with the treatm
ent of twenty-five infections (in twenty-five patients) after total el
bow arthroplasty and to examine indications for salvage of the prosthe
sis compared with those for resection arthroplasty. The patients were
divided into three groups on the basis of treatment, Group I comprised
fourteen patients who were managed with multiple, extensive irrigatio
n and debridement procedures with retention of the original components
. The primary indication for retention of the prosthesis was evidence
that it was well fixed as determined both radiographically and intraop
eratively. Group II comprised six patients who had removal of the pros
thesis and debridement followed by immediate or staged reimplantation.
Group III comprised five patients who were managed with resection art
hroplasty. The infection was successfully eradicated in seven of the f
ourteen elbows that had salvage of the prosthesis with irrigation and
debridement. The results were strongly dependent on the causative orga
nism; attempts at debridement failed in the four elbows that were infe
cted with Staphylococcus epidermidis compared with three of the ten th
at were infected with another organism. Four of the six patients in Gr
oup II had successful reimplantation of a prosthesis; in three, the in
fection had been caused by an organism other than Staphylococcus epide
rmidis, Only one of the three patients who had a Staphylococcus epider
midis infection had a successful reimplantation, None of the five pati
ents who had a resection arthroplasty had signs of infection at the la
test follow-up examination. We concluded that salvage of the prosthesi
s with extensive irrigation and debridement in the presence of an infe
ction about the elbow can be reasonably successful if the infecting or
ganism is not Staphylococcus epidermidis and if the components are wel
l fixed. When removal of the components is warranted, staged reimplant
ation can also be highly successful when the infecting organism is not
Staphylococcus epidermidis. However, the repeated operations necessar
y to retain a prosthesis and the high rates of complications seen with
this approach - and the relatively good rates of satisfaction obtaine
d with resection arthroplasty - suggest that resection arthroplasty re
mains the procedure of choice in medically frail patients or in patien
ts for whom function of the elbow is less of a concern.