ESTIMATION OF NONLINEAR COUPLINGS ON THE BASIS OF COMPLEXITY AND PREDICTABILITY - A NEW METHOD APPLIED TO CARDIORESPIRATORY COORDINATION

Nonlinear coordination is an essential property of the complex functio ning of the autonomic nervous system. Therefore, the coupled behavior of heart rate fluctuations (HRF) and respiratory movements (RM) was an alyzed on the basis of their joint reconstruction in the phase space. Independence measures of complexity and predictability were approximat ed from the correlation integrals which enabled the strength of cardio respiratory couplings to be quantified. These measures were validated in a simulation study of two coupled nonlinear oscillators in dependen ce on their coupling strength and respective synchronization effects. The cardiorespiratory coordination during quiet sleep and active sleep of newborn piglets was quantified by means of the proposed independen ce measures of complexity and predictability. The difference of those measures between the sleep states investigated was more significant th an the difference of the respective linear coherence peaks.