The purpose of the work is to calculate basic dosimetry data for a Var
iSource high dose rate Ir-192 source in water. These basic dosimetry d
ata, expressed in the dose calculation formalism endorsed by the Inter
stitial Collaborative Working Group and AAPM Task group 43, include th
e dose rate constant, the radial dose function, and the anisotropy fun
ction. A modified version of the EGS4 Monte Carlo code was used to cal
culate (1) the transverse-axis dose distribution at radial distances f
rom 0.1 to 14 cm, (2) the two-dimensional dose distribution for axial
and radial distances from 0.1 cm to 10 cm, and (3) the air-kerma stren
gth, for the VariSource high dose rate Ir-192 source. From these Monte
Carlo results the basic dosimetry data were derived. The calculated d
ose rate constant for the high dose rate source is 1.044+/-0.2% cGy h(
-1) per unit air-kerma strength. The anisotropy function exhibits 40%-
60% deviations from isotropy at positions on the long axis. The radial
dose function for the source is nearly identical to that for a microS
electron high dose rate Ir-192 source, except at radial distances smal
ler than 0.5 cm where values for VariSource are 1.7%-2.8% smaller. The
se basic dosimetry data were compared with corresponding results from
other authors for high and low dose rate Ir-192 sources, as well as wi
th Meisberger's fitting formula. (C) 1998 American Association of Phys
icists in Medicine. [S0094-2405(98)01404-7].