BENIGN FIBROMATOUS TUMOR (FIBROMA) OF THE KIDNEY - A CASE-REPORT

Citation
G. Magro et al., BENIGN FIBROMATOUS TUMOR (FIBROMA) OF THE KIDNEY - A CASE-REPORT, Pathology research and practice, 194(2), 1998, pp. 123-127
Citations number
18
Categorie Soggetti
Pathology
ISSN journal
03440338
Volume
194
Issue
2
Year of publication
1998
Pages
123 - 127
Database
ISI
SICI code
0344-0338(1998)194:2<123:BFT(OT>2.0.ZU;2-O
Abstract
Benign fibromatous tumor (fibroma) of the urogenital tract is a distin ctive pathologic entity occurring in the testis, paratesticular struct ures and renal peripelvis. We report a well-circumscribed tumor replac ing the cortex and the medulla of more than half of the upper kidney, radiographically thought to be renal cell carcinoma. Histologically, t he tumor was characterized by a variable cellularity and was composed of bland spindle-shaped cells loosely dispersed in a fibromyxoid to de nsely fibrous stroma in which calcifications and chronic inflammation were not observed. Immunocytochemistry showed that cells were positive for vimentin and, only focally, stained positive for desmin and alpha -smooth muscle actin. Differential diagnosis included a wide spectrum of benign and malignant spindle cell tumors. The clinicopathologic fea tures were consistent with benign fibromatous tumor (fibroma) of the k idney. To our knowledge, this is the first case of benign fibromatous tumor (fibroma) of the kidney reported in the English literature.