E. Bucciarelli et al., SPONTANEOUS DISSECTING ANEURYSM OF CORONARY-ARTERY IN A PREGNANT WOMAN AT TERM, Pathology research and practice, 194(2), 1998, pp. 137-139
We describe a case of spontaneous dissecting aneurysm of the circumfle
x coronary artery in a 44-year-old primigravida at term with no vascul
ar risk factors. Spontaneous coronary artery dissection is a very rare
condition with a greater prevalence in women, postpartum in particula
r. The left anterior descending artery is the most frequently affected
. Histologically, the most common finding is a hematoma occupying the
outer third of the media, resulting in complete compression of the tru
e lumen. Arterial wall changes during pregnancy together with hemodyna
mic factors, a lytic action of protease released from eosinophils, and
intimal tears an the main hypotheses considered to explain the etiolo
gy of spontaneous coronary artery dissection.