K. Berek et al., POLYNEUROPATHY DEVELOPING IN CRITICALLY I LL PATIENTS - CRITICAL ILLNESS POLYNEUROPATHY, Wiener Klinische Wochenschrift, 110(7), 1998, pp. 243-252
Polyneuropathy developing in critically ill patients (''critical illne
ss polyneuropathy'' - CIP) is diagnosed with increasing frequency in i
ntensive care units. CIP is an axonal polyneuropathy leading to diffic
ulties in weaning from artificial ventilation and symmetrical flaccid
tetraparesis. Pathogenetically CIP is considered to be part of the mul
tiple organ dysfunction syndrome (MODS) in the course of sepsis or sys
temic inflammatory response syndrome (SIRS). The incidence of CIP in s
eptic patients with MODS ranges from 50% to 70%. Electroneurography (E
NG) and electromyography (EMG) are essential diagnostic procedures. Th
e mortality in patients with CIP is higher than in patients without CI
P. Depending on the severity of CIP, recovery of neurological function
in survivors is usually relatively good.