I. Kukita et al., INHALED NITRIC-OXIDE FOLLOWED BY EXTRACORPOREAL MEMBRANE-OXYGENATION IN RESUSCITATING A NEWBORN WITH HYPOXEMIA, Acta Paediatrica Japonica Overseas Edition, 40(1), 1998, pp. 91-92
In a newborn requiring cardiopulmonary resuscitation because of hypoxe
mia due to sepsis (oxygenation index > 40), inhalation of nitric oxide
(NO) in a concentration of 16 p.p.m. improved oxygenation and restore
d spontaneous circulation. Cannulation for extracorporeal membrane oxy
genation (ECMO) then was performed safely under NO inhalation. ECMO wa
s discontinued on day 7, and on day 14 the infant was extubated. Durin
g follow-up examination at 5 months of age no neurological abnormaliti
es were found. This case shows the usefulness of combining inhaled NO
and ECMO.