Preterm infants are at high risk of severe community acquired infectio
ns. In particular viral respiratory infections, mainly respiratory syn
citial virus infections (RVS), are responsible for a high incidence of
rehospitalizations of preterm infants during their 2 first years of l
ife. Prevention relies upon 1/ the application of an immunization prog
ram identical to the program applied to normal term infants, a cardior
espiratory monitoring during 48-72 hours following immunization being
recommended in those infants who carry a risk of recurrent apnea; 2/ g
eneral measures with a demonstrated protective effect, ie, breast feed
ing, elimination of smoking at home, and when possible limitation of c
ontacts with infant and children communities. Immunoprophylaxis agains
t RVS infectiosn has been shown to be effective in reducing the severi
ty of RVS infections in preterm infants but is presently not available
in European countries.