S. Aksoylar et al., EVALUATION OF SPONGING AND ANTIPYRETIC MEDICATION TO REDUCE BODY-TEMPERATURE IN FEBRILE CHILDREN, Acta Paediatrica Japonica Overseas Edition, 39(2), 1997, pp. 215-217
Two hundred and twenty-four children aged 6 months to 5 years, with re
ctal temperatures greater than or equal to 39 degrees C (104 degrees F
), were randomly treated with sponging alone or with medication includ
ing a single oral dose of aspirin 15 mg/kg, or paracetamol 15 mg/kg, o
r ibuprofen 8 mg/kg. Twenty-three children were excluded from the fina
l analysis because they did not complete the study. Demographic charac
teristics of the patients were found to be comparable in all groups. R
ectal temperatures were recorded every 30 min for a 3 h period. During
the first 30 min of intervention, sponging was found to be more effec
tive than all of the three medications. After 60 min, the effects of e
ach medication became superior to sponging with tepid water in reducin
g body temperature. Twenty-three children were excluded from the final
analysis because they did not complete the study. Comparing the effec
t of the three different medications, it was seen that the antipyretic
efficacy of aspirin and ibuprofen were significantly more than parace
tamol 3 h after intervention (P < 0.05). For the management of fever o
ver 39 degrees C, it is therefore recommended to give children an anti
pyretic drug, preferably ibuprofen, and at the same time to begin spon
ging to provide a rapid and sustained antipyresis.