THE SYNTHESIS AND BIOLOGICAL-ACTIVITY OF N-(1,6-DIMETHOXY-2-PYRIMIDINYL)-N'-PHOSPHORYL UREA DERIVATIVES

In this paper ,6-dimethoxy-2-pyrimidinyl)-N'-dichloro-phosphoryl urea (1) was synthesized by addition reaction of dichloro-phosphoryl isocya nate with 4,6-dimethoxy-2-aminopyrimidine. Compound I reacted with two equivalents of amines or alcohols to obtain symmetric disubstituted p hosphoryl urea derivatives II a - II i, and reacted with one equivalen t of amines to give monochlorophosphoryl ureas III a - III e which rea cted with one equivalent of alcohols to obtain asymmetric disubstitute d phosphoryl urea derivatives IV a - IV g. The biological tests indica ted that compounds II, III and IV showed herbicidal activities.