INOSITOL HAS BEHAVIORAL-EFFECTS WITH ADAPTATION AFTER CHRONIC ADMINISTRATION

Authors
COHEN H KOTLER M ZAPLAN Z MATAR MA KOFMAN O BELMAKER RH
Citation
H. Cohen et al., INOSITOL HAS BEHAVIORAL-EFFECTS WITH ADAPTATION AFTER CHRONIC ADMINISTRATION, Journal of neural transmission, 104(2-3), 1997, pp. 299-305
Citations number
32
Categorie Soggetti
Clinical Neurology",Neurosciences
Journal title
Journal of neural transmission → ACNP
ISSN journal
03009564
Volume
104
Issue
2-3
Year of publication
1997
Pages
299 - 305
Database
ISI
SICI code
0300-9564(1997)104:2-3<299:IHBWAA>2.0.ZU;2-B
Abstract
Inositol is a simple dietary polyol that serves as a precursor in impo rtant second messenger systems. Inositol in pharmacological doses has been reported recently to be therapeutic in depression, panic disorder and obsessive compulsive disorder. We hereby report effects of inosit ol in the elevated plus maze model of anxiety. These results should al low development of new inositol analogs that could expand psychoactive drug development possibilities via second messenger manipulation.