The measurement of short distances by interferometry using low coheren
ce light is a potential option in the study of interfaces between intr
aocular elements. In this article we describe an experimental device t
o measure the distance between such interfaces in vitro. The procedure
utilizes a Michelson interferometer to generate the probe beams toget
her with a silicate photodetector system and a lock-in synchronous amp
lifier. The cornea and crystalline lens thickness of a rabbit eyeball
are evaluated, as well as the human cornea in preservative solution. T
hese tests indicate the method to be efficient, easy-to-handle, of hig
h resolution and to present a signal-to-noise ratio of up to 12. We co
nsider the possibility of its use in obtaining information about the d
egeneration of intraocular structures during the preservation process.
(C) 1998 American Institute of Physics.